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RAB7A Rabbit pAb(bs-6703R)-50u

l/100ul
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  • ¥1180 - 1980
  • Bioss已认证
  • bs-6703R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    产品编号bs-6703R
    英文名称RAB7A Rabbit pAb
    中文名称RAS癌基因相关蛋白RAB7抗体
    英文别名RAB7A_HUMAN; Ras-related protein Rab-7a; EC:3.6.5.2; RAB7;
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse (Rat)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human RAB7A
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量23 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation

    Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Ras Family

    Tags & Cell Markers > Subcellular Markers > Organelles > Endosome

    Tags & Cell Markers > Subcellular Markers > Organelles > Lysosome

    亚基Interacts with RILP. Interacts with PSMA7. Interacts with RNF115. Interacts with FYCO1
    亚细胞定位Late endosome. Lysosome. Cytoplasmic vesicle, phagosome. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    组织特异性Widely expressed; high expression found in skeletal muscle.
    相似性Belongs to the small GTPase superfamily. Rab family.
    功能Involved in late endocytic transport. Contributes to the maturation of phagosomes (acidification).
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Members of the RAB family of RAS related GTP binding proteins are important regulators of vesicular transport and are located in specific intracellular compartments. RAB7 has been localized to late endosomes and shown to be important in the late endocytic pathway. In addition, it has been shown to have a fundamental role in the cellular vacuolation induced by the cytotoxin VacA of Helicobacter pylori.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Lane 1: Mouse Cerebrum tissue lysates
    Lane 2: Mouse Lung tissue lysates
    Lane 3: Human HeLa cell lysates
    Lane 4: Human A431 cell lysates
    Lane 5: Human HL-60 cell lysates
    Primary: Anti-RAB7 (bs-6703R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 23 kDa
    Observed band size: 21 kDa

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    图标文献和实验
    该产品被引用文献

    [IF={{ 8 }}] {Dixit, Saurabh, et al. "Caveolin-mediated endocytosis of the Chlamydia M278 outer membrane peptide encapsulated in poly (lactic acid)-Poly (ethylene glycol) nanoparticles by mouse primary dendritic cells enhances specific immune effectors mediated by MHC class II and CD4+ T cells." Biomaterials (2017).} {ICC} {="Mouse"}

    [IF={{ 7.546 }}] {Luo R et al. Clostridium perfringens beta2 toxin induced in vitro oxidative damage and its toxic assessment in porcine small intestinal epithelial cell lines. Gene. 2020 Oct 30;759:144999.} {WB} {Rat}

    [IF={{ 7.546 }}] {Zixuan Liu. et al. Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation. Part Fibre Toxicol. 2020 Dec;17(1):1-17} {WB} {Rat}

    [IF={{ 6.656 }}] {Ye Yang. et al. Neocryptotanshinone protects against myocardial ischemia-reperfusion injury by promoting autolysosome degradation of protein aggregates via the ERK1/2-Nrf2-LAMP2 pathway. PHYTOMEDICINE. 2023 Feb;110:154625} {WB} {Rat}

    [IF={{ 4.7 }}] {Joshua Williams. et al. Genetic Engineering of Bacteriophage K1F with Human Epidermal Growth Factor to Enhance Killing of Intracellular E. coli K1. ACS SYNTH BIOL. 2023;XXXX(XXX):XXX-XXX} {IF} {Human}

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    文献支持
    RAB7A Rabbit pAb(bs-6703R)-50ul/100ul
    ¥1180 - 1980