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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-1773R |
| 英文名称 | Follistatin Rabbit pAb |
| 中文名称 | 促卵泡激素抑释素/卵泡抑素抗体 |
| 英文别名 | Activin binding protein; FS; Follistatin; Activin-binding protein; FS; fst; FST_HUMAN; Human follistatin gene; follistatin isoform FST344 precursor; FST344; follistatin isoform FST317 precursor; FST317; FST_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat (Chicken, Dog, Pig, Cow, Horse, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Follistatin |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 38 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Polymerase associated factors > Pol II Transcription Signal Transduction > Growth Factors/Hormones > Hormones |
| 亚基 | Monomer (Potential). |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid. |
| 相似性 | Contains 3 follistatin-like domains. Contains 3 Kazal-like domains. Contains 1 TB (TGF-beta binding) domain. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. There is evidence linking polycystic ovary syndrome and follistatin. Follistatin binds directly to activin and functions as an activin antagonist. It specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Lane 1: Mouse Pituitary tissue lysates
Lane 2: Mouse Placenta tissue lysates
Lane 3: Rat Pituitary tissue lysates
Lane 4: Rat Placenta tissue lysates
Lane 5: Rat Breast tissue lysates
Primary: Anti-Follistatin (bs-1773R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kD
Observed band size: 47 kD
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文献和实验= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
内源性FSTL1 通过激活钠‐钾泵引起膜超极化调节痛觉信息传递
‐钾泵活性;然而,人体内是否存在钠‐钾泵的内源性的激动剂还不清楚。 近日,中科院上海生科院神经所张旭实验室通过对背根神经节(dorsal root ganglion,DRG)的研究,发现在 DRG 中有一种选择性高表达的蛋白——滤泡素抑制素样蛋白 1(Follistatin‐like 1,FSTL1)能通过清亮小泡运输至脊髓内的传入神经末端释放,并直接与传入神经末端突触前膜上的钠‐钾泵 α1 亚基相结合,增强钠‐钾泵活性,使细胞膜超极化,从而对传入神经末端的兴奋性突触传递起抑制
Intraspinal Transplantation of Mouse and Human Neural Precursor Cells
. no. X100) Antibodies: Nestin (rabbit polyclonal; Millipore, cat. no. ABD69
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