Sample:
HepG2(Human) Cell Lysate at 30 ug
Primary: Anti-CD137 (bs-2449R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 25 kD
Observed band size: 39 kD
- ￥1180 - 2800
- Bioss
- bs-2449R
- 2025年10月24日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
PKC delta Rabbit pAb, BF647 conjugated(bs-23441R-BF647)-100ul
￥2980
TRIM5 gamma Rabbit pAb(bs-16745R)-50ul/100ul/200ul
￥1180FCGRT Rabbit pAb, PE-Cy5.5 conjugated(bs-13151R-PE-Cy5.5)-100ul
￥2980TMCC1 Rabbit pAb, AP conjugated(bs-19948R-AP)-100ul
￥2980phospho-NFAT2 (Ser233) Rabbit pAb, Biotin conjugated(bs-19785R-Bio)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-2449R |
| 英文名称 | CD137 Rabbit pAb |
| 中文名称 | 肿瘤坏死因子受体超家族成员9抗体 |
| 英文别名 | Tumor necrosis factor receptor superfamily member 9; TNFRSF9; 4-1BB; 4 1BB; 4 1BB ligand receptor; Homolog of mouse 4 1BB; Receptor protein 4 1BB; T cell antigen 4 1BB homolog; T cell antigen ILA; CDw137; CD 137; CD137 antigen; Induced by lymphocyte activation; ILA; Interleukin activated receptor homolog of mouse Ly63; Ly63; MGC2172; MGC114552; OTTHUMP00000044294; TNR9_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CD137 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 25 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with TRAF1, TRAF2 and TRAF3. Interacts with LRR-repeat protein 1/LRR-1. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed on the surface of activated T-cells. |
| 相似性 | Contains 4 TNFR-Cys repeats. |
| 功能 | Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CD137 exists on the cell surface as a monomer with a molecular mass of 30 kDa and as a dimer of 55 kDa. Human and mouse CD137 share 60% amino acid identity. CD137 (4-1BB), a member of the tumour necrosis factor receptor superfamily, is a type I transmembrane glycoprotein expressed on the cell surface of activated splenic T cells and thymocytes. The functions of CD137 in T lymphocytes include regulating activation, proliferation and apoptosis. CD137 and CD28 are costimulatory molecules of T cell activation. Costimulatory molecules are important in initiating anti-tumor immune responses. CD137 plays an important role in regulating T-cell-dependent immune responses. Expression of CD137 correlates negatively with lymphocyte proliferation and positively with the degree of activation-induced cell death caused by mitogen overstimulation. In monocytes, CD137 induces activation, promotes adherence and prolongs survival. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
Lane 1: Mouse Thymus Lysates
Lane 2: Mouse Spleen Lysates
Lane 2: Mouse Lymph Lysates
Primary: Anti-CD137 (bs-2449R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 25kDa
Observed band size: 42kDa
Lane 1: Mouse Thymus Lysates
Lane 2: Mouse Spleen Lysates
Lane 2: Mouse Lymph Lysates
Primary: Anti-CD137 (bs-2449R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 25kDa
Observed band size: 42kDa
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
[IF={{ 8.38 }}] {Daquinag, A. C., et al. "Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development." Cell Death & Differentiation (2014).} {Other} {="Mouse"}
[IF={{ 3.79 }}] {Claycombe, Kate J., et al. "Decreased beige adipocyte number and mitochondrial respiration coincide with increased histone methyl transferase (9Ga) and reduced FGF21 gene expression in Sprague Dawley rats fed prenatal low protein and postnatal high fat diets." The Journal of Nutritional Biochemistry (2016).} {FCM} {="Rat"}
[IF={{ 3.743 }}] {Lei W et al. Phthalides, senkyunolide A and ligustilide, show immunomodulatory effect in improvingatherosclerosis, through inhibiting AP-1 and NF-κB expression. Biomed Pharmacother. 2019 Jun 6;117:109074.} {WB} {Mouse}
相关实验
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
Theoretical Aspects of the Quantitative Characterization of Ligand Binding
dependences of the binding function ( r ) upon free ligand concentration ( C S ) for various types of acceptor‐ligand interaction. Rectangular hyperbolic dependence (—) for an acceptor with two equivalent and independent sites ( K AS = K 1 = K 2 = K 3 = K
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
技术资料暂无技术资料 索取技术资料
文献支持
CD137 Rabbit pAb(bs-2449R)-50ul/100ul/200ul
￥1180 - 2800
