Sample:
Lane 1: Human HUVEC cell lysates
Lane 2: Human U-2 OS cell lysates
Lane 3: Human A549 cell lysates
Primary: Anti-ESM1 (bs-3615R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 43-47 kDa
- ￥1180 - 2800
- Bioss
- bs-3615R
- 2025年10月24日
- 产品信息以Bioss网站为准
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-3615R |
| 英文名称 | ESM1 Rabbit pAb |
| 中文名称 | 内皮细胞特异性分子1抗体 |
| 英文别名 | Endocan; Endothelial cell specific molecule 1; ESM 1; ESM-1; ESM 1 secretory protein; ESM1 secretory protein; ESM1_HUMAN; Endothelial cell-specific molecule 1. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Pig, Cow, Horse) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ESM1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 20 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Tags & Cell Markers > Cell Type Markers > Epi / Endo-thelial |
| 亚基 | Monomer. |
| 亚细胞定位 | Secreted. Peroxisome. |
| 组织特异性 | Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney. |
| 翻译后修饰 | May contain intrachain disulfide bonds. |
| 相似性 | Contains 1 IGFBP N-terminal domain. |
| 功能 | May have potent implications in lung endothelial cell-leukocyte interactions. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ESM1 is a secreted dermatan sulfate proteoglycan which is predominantly expressed in the endothelial cells in human lung and kidney tissues. Expression of ESM1 is regulated by cytokines. ESM1 may have a role in lung endothelial cell-leukocyte interactions. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 8.897 }}] {Wu, Qingsi. et al. Targeted delivery of celastrol to glomerular endothelium and podocytes for chronic kidney disease treatment. Nano Res. 2021 Dec;:1-13} {IF} {Mouse}
[IF={{ 4.522 }}] {Zhao H et al. miR‐181a/b‐5p ameliorates inflammatory response in monocrotaline‐induced pulmonary arterial hypertension by targeting endocan. J Cell Physiol. 2019 Oct 21.} {IF,ICC} {Rat}
[IF={{ 1.6 }}] {Hemida Aiat Shaban. et al. EpCAM, Ki67, and ESM1 Predict Hepatocellular Carcinoma Recurrence After Liver Transplantation. APPL IMMUNOHISTO M M. 2023 Sep;31(9):596} {IHC} {Human}
[IF={{ 0 }}] {Farahlina Baba. et al. Endocan-microvascular Density in Primary Ovarian Carcinoma. Asian Pac J Cancer P. 2022 Mar 1;23(3):929-935} {IHC} {Human}
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ESM1 Rabbit pAb(bs-3615R)-50ul/100ul/200ul
￥1180 - 2800
