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- bs-11129R
- 2025年10月16日
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-11129R |
| 英文名称 | Caspr2 Rabbit pAb |
| 中文名称 | 轴突相关CNTP2蛋白抗体（少突胶质细胞） |
| 英文别名 | Cell recognition molecule Caspr2; Cntnap2; CNTP2; CNTP2_HUMAN; Contactin-associated protein-like 2. |
| 产品应用 | WB=1:500-2000, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | Human, Rat |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Caspr2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 145 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Cell Type Marker > Glia marker > Oligodendrocyte marker |
| 亚基 | Associates with KCNA2. |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Predominantly expressed in nervous system. |
| 相似性 | Belongs to the neurexin family. Contains 2 EGF-like domains. Contains 1 F5/8 type C domain. Contains 1 fibrinogen C-terminal domain. Contains 4 laminin G-like domains. |
| 功能 | May play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the juxtaparanodal region of the axo-glial junction. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | bs-11129P is one synthetic peptide derived from human Caspr2. CASPR is a transmembrane glycoprotein of the neurexin superfamily that is highly enriched in regions of myelinated axons. The axons of myelinated nerves in the adult nervous system possess specialized subcellular structures essential for efficient and rapid action potential propagation. CASPR and the closely related molecule CASPR2, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), demarcate distinct subdomains in myelinated axons. While CASPR is present at the paranodal junctions, CASPR2 is precisely colocalized with Shaker-like K+ channels in the juxtaparanodal region. CASPR2 specifically associates with Kv1.1, Kv1.2, and their Kvbeta2 subunit. CASPR family members may play a role in the local differentiation of the axon into distinct functional subdomains. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {ELISA} | {1:5000-10000} |
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文献和实验= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
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