NCR1 | NKp46/CD335 Rabbit pAb(bs-10027R)-50ul/100ul/200ul产品图
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NCR1 | NKp46/CD335 Rabbit pAb(

bs-10027R)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-10027R
  • 2026年10月13日
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-10027R
    英文名称NCR1 Rabbit pAb
    中文名称细胞毒性受体NK-p46抗体
    英文别名Natural killer cell p46-related protein; Natural cytotoxicity triggering receptor 1; NK-p46; NKp46; NK cell-activating receptor; Lymphocyte antigen 94 homolog; CD335; CD 335; LY94; NCTR1_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat (Dog, Pig, Cow, Horse, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CD335
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量31 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Adaptive Immunity > T Cells > Cytotoxic Cells

    Signal Transduction > Adapters > Transmembrane

    亚基Interacts with CD247 and FCER1G
    亚细胞定位Cell membrane.
    组织特异性Selectively expressed by both resting and activated NK cells.
    翻译后修饰N-glycosylated.
    _x000D_ O-glycosylated.
    相似性Belongs to the natural cytotoxicity receptor (NCR) family.
    _x000D_ Contains 2 Ig-like (immunoglobulin-like) domains.
    功能Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    _x000D_ Lane 1: Mouse Spleen tissue lysates
    _x000D_ Lane 2: Mouse Lung tissue lysates
    _x000D_ Lane 3: Rat Lymph node tissue lysates
    _x000D_ Lane 4: Human HL-60 cell lysates
    _x000D_ Primary: Anti-NCR1 (bs-10027R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 31 kDa
    _x000D_ Observed band size: 48 kDa
    产品细节图片2
    Sample:
    _x000D_ Kidney (Mouse) Lysate at 40 ug
    _x000D_ Spleen (Mouse) Lysate at 40 ug
    _x000D_ Lymph node (Mouse) Lysate at 40 ug
    _x000D_ A431(Human) Cell Lysate at 30 ug
    _x000D_ Raji(Human) Cell Lysate at 30 ug
    _x000D_ Primary: Anti- NCR1 (bs-10027R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 31 kD
    _x000D_ Observed band size: 46 kD

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    NCR1 | NKp46/CD335 Rabbit pAb(bs-10027R)-50ul/100ul/200ul
    ¥1180 - 2800