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| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-2576R |
| 英文名称 | Ly-6G Rabbit pAb |
| 中文名称 | 淋巴细胞抗原6G抗体 |
| 英文别名 | Gr-1; Gr1; Ly 6G; Ly-6G.1; Ly6G; lymphocyte antigen 6 complex locus G; Lymphocyte antigen 6G. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse Ly-6G/Gr-1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 14 kDa |
| 实际分子量 | 21-25 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Stem Cells > Hematopoietic Progenitors > Myeloid > Monocytic Lineage Stem Cells > Hematopoietic Progenitors > Myeloid > Neutrophil Lineage Stem Cells > Hematopoietic Progenitors > Surface Molecules Tags & Cell Markers > Cell Type Markers > Other Cell Types |
| 亚细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor (By similarity). |
| 组织特异性 | Expressed in bone marrow. |
| 相似性 | Contains 1 UPAR/Ly6 domain. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Ly6G is a GPI-anchored protein, that is also known as the myeloid differentiation antigen Gr1. The antigen is transiently expressed on monocytes in the bone marrow. The level of antigen expression in the bone marrow directly correlates with granulocyte differentiation and maturation. Ly6G is expressed predominantly on neutrophils, also in a subset of eosinophils, differentiating pre-monocytes, and plasmacytoid dendritic cells. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Primary: Anti-Ly-6G (bs-2576R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 14 kDa
Observed band size: 18 kDa
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文献和实验[IF={{ 6.17 }}] {Ying Xu. et al. PINK1-mediated mitophagy protects against hepatic ischemia/reperfusion injury by restraining NLRP3 inflammasome activation. Free Radical Bio Med. 2020 Nov;160:871} {IF,IHC} {Mouse}
[IF={{ 5.3 }}] {Tian Huang. et al. Gr-1 blockade remodels the immunosuppressive microenvironment induced by incomplete microwave ablation of hepatocellular carcinoma. CANCER CELL INT. 2024 Dec;24:395} {IF} {Mouse}
[IF={{ 4.12 }}] {Arecco et al. Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation. (2016) Sci.Rep. 6:24708} {IF} {Mouse}
[IF={{ 2.319 }}] {Xinhong WANG. et al. Anti-inflammatory effect of HGF responses to oral traumatic ulcers using an HGF-Tg mouse model. 2021 Nov 25} {IHC} {Mouse}
[IF={{ 16.264 }}] {Schukur, Lina, et al. "Implantable synthetic cytokine converter cells with AND-gate logic treat experimental psoriasis." Science Translational Medicine7.318 (2015): 318ra201-318ra201.} {IHC} {="Mouse"}
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