CALCA | CALC1/CGRP1 Rabbit pAb(bs-18210R)-50ul/100ul/200ul产品图
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CALCA | CALC1/CGRP1 Rabbit pAb

(bs-18210R)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-18210R
  • 2026年10月13日
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-18210R
    英文名称Calcitonin Rabbit pAb
    中文名称降钙素抗体
    英文别名alpha CGRP; CALC 1; CALC A; CALC1; CALCA; Calcitonin related polypeptide alpha; CGRP 1; CGRP; CGRP I; CGRP-1; CGRPI; CGRP1; CT; Katacalcin; KC; MGC126648; alpha type CGRP; calcitonin 1; calcitonin gene related peptide 1; calcitonin gene related peptide I; calcitonin isoform CT preproprotein.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Dog, Rabbit, GuineaPig)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Calcitonin
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量3.5/13 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Growth factors > Hormones

    Cancer > Tumor biomarkers > Hormones

    Signal Transduction > Growth Factors/Hormones > Hormones

    亚细胞定位Secreted.
    相似性Belongs to the calcitonin family.
    功能The level of procalcitonin in the blood stream of healthy individuals is below the limit of detection (0.01 µg/L) of clinical assays. The level of procalcitonin rises in a response to a proinflammatory stimulus, especially of bacterial origin. It does not rise significantly with viral or non-infectious inflammations. With the derangements that a severe infection with an associated systemic response brings, the blood levels of procalcitonin may rise to 100 µg/L. In serum, procalcitonin has a half-life of 25 to 30 hours. Remarkably the high procalcitonin levels produced during infections are not followed by a parallel increase in calcitonin or a decrease in serum calcium levels.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Procalcitonin (PCT) is a peptide precursor of the hormone calcitonin, the latter being involved with calcium homeostasis. It arises once preprocalcitonin is cleaved by endopeptidase. It is composed of 116 amino acids and is produced by parafollicular cells (C cells) of the thyroid and by the neuroendocrine cells of the lung and the intestine.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    P‌‌araformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Calcitonin) Polyclonal Antibody, Unconjugated (bs-18210R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    产品细节图片2
    Sample:
    _x000D_ Cerebrum (Mouse) Lysate at 40 ug
    _x000D_ Primary: Anti-Calcitonin (bs-18210R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 3.5/13 kD
    _x000D_ Observed band size: 17 kD

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    图标文献和实验
    该产品被引用文献

    [IF=7.3] Aida Maddahi. et al. Sex differences in expression of CGRP family of receptors and ligands in the rat trigeminal system. J HEADACHE PAIN. 2024 Nov;25(1):193 IHC Rat

    [IF=4.132] Xiang, Chengyu. et al. Fasudil Ameliorates Osteoporosis Following Myocardial Infarction by Regulating Cardiac Calcitonin Secretion. J CARDIOVASC TRANSL. 2022 May;:1-14 IHC Mouse

    [IF=1.834] Fang Dai. et al. Effects of long term diabetogenic high fat diet on bone in ovariectomized female rats. BIOTECH HISTOCHEM. 2022 Jun 28 IHC Rat

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    文献支持
    CALCA | CALC1/CGRP1 Rabbit pAb(bs-18210R)-50ul/100ul/200ul
    ¥1180 - 2800