Sample: K562 Cell (human) Lysate at 40 ug
_x000D_
Primary: Anti-KCNT1 (bs-20327R) at 1/300 dilution
_x000D_
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_
Predicted band size: 137 kD
_x000D_
Observed band size: 137 kD
_x000D_
- ￥1180 - 2800
- Bioss
- bs-20327R
- 2026年10月13日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-20327R |
| 英文名称 | KCNT1 Rabbit pAb |
| 中文名称 | 钾离子通道亚家族T成员1抗体 |
| 英文别名 | bA100C15.2; EIEE14; ENFL5; KCa4.1; KCNT1; KCNT1_HUMAN; Potassium channel subfamily T member 1; Potassium channel, subfamily T, member 1; SLACK. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human KCNT1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 137 kDa |
| 浓度 | 1mg/ml |
| 储存液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle. |
| 翻译后修饰 | Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain increases channel activity. |
| 相似性 | Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily. _x000D_ Contains 1 RCK N-terminal domain. |
| 功能 | Outwardly rectifying potassium channel subunit that may co-assemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro). |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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KCNT1 Rabbit pAb(bs-20327R)-50ul/100ul/200ul
￥1180 - 2800
