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- 技术资料
- 规格:
50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-4391R |
| 英文名称 | ZMIZ2 Rabbit pAb |
| 中文名称 | 锌指MIZ结构域蛋白2抗体 |
| 英文别名 | 2410117E06Rik; D11Bwg0280e; DKFZp761I2123; hZIMP7; KIAA1886; PIAS like protein Zimp7; PIAS-like protein Zimp7; R74931; RGD1309256; RP23-198N14.8; ZIMP7; Zinc finger MIZ domain containing protein 2; Zinc finger MIZ domain-containing protein 2; Zinc finger MIZ type containing 2; zinc finger, MIZ-type containing 2; zinc finger, MIZtype containing2; ZMIZ 2; Zmiz2; ZMIZ2_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ZMIZ2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 97 kDa |
| 浓度 | 1mg/ml |
| 储存液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Remodeling > Swi / Snf Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Testosterone Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger Signal Transduction > Signaling Pathway > Nuclear Signaling > Nuclear Hormone Receptors > Testosterone |
| 亚细胞定位 | Nucleus. Detected at replication foci throughout S phase. |
| 组织特异性 | Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary. |
| 相似性 | Contains 1 SP-RING-type zinc finger. |
| 功能 | Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |

Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZMIZ2) Polyclonal Antibody, Unconjugated (bs-4391R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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ZMIZ2 | ZIMP7 Rabbit pAb(bs-4391R)-50ul/100ul/200ul
¥1180 - 2800






