Sample:
Brain (Mouse) Lysate at 40 ug
Primary: Anti-PDS5B (bs-12605R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 165 kD
Observed band size: 165 kD
- ￥1180 - 2800
- Bioss
- bs-12605R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-12605R |
| 英文名称 | PDS5B Rabbit pAb |
| 中文名称 | 雄激素诱导细胞增殖抑制蛋白抗体 |
| 英文别名 | AI646570; Androgen induced proliferation inhibitor; Androgen-induced prostate proliferative shutoff associated protein AS3; APRIN; AS3; AW212954; CG008; FLJ23236; KIAA0979; mKIAA0979; PDS5, regulator of cohesion maintenance, homolog B(S. cerevisiae); Pds5b; RP1 267P19.1; Sister chromatid cohesion protein PDS5 homolog B. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PDS5B |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 165 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Chromatid Cohesion |
| 亚基 | Interacts with the cohesin complex. Interacts with RAD21; the interaction is direct. Interacts with WAPAL (via FGF motifs) or CDCA5 (via the FGF motif); the interaction is direct, cohesin-dependent and competitive (Probable). |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Widely expressed. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Belongs to the PDS5 family. Contains 3 A.T hook DNA-binding domains. Contains 1 HEAT repeat. |
| 功能 | Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein that interacts with the conserved protein complex termed cohesion. The cohesion complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. [provided by RefSeq, May 2010]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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PDS5B Rabbit pAb(bs-12605R)-50ul/100ul/200ul
￥1180 - 2800
