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METTL4 Rabbit pAb(bs-18851R)-5

0ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-18851R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-18851R
    英文名称METTL4 Rabbit pAb
    中文名称甲基化样蛋白4抗体
    英文别名FLJ11350; methyltransferase like 2; Methyltransferase like 2B; Methyltransferase-like protein 2B; METL; METTL2; METTL2A; PSENIP1.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse, Rat (Human, Dog, Horse, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human METTL4
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量54 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > Methylated DNA

    Epigenetics and Nuclear Signaling > DNA methylation > DNMTs

    Epigenetics and Nuclear Signaling > DNA methylation > Methylated DNA Associated

    Tags & Cell Markers > Subcellular Markers > Nucleus > Other Nuclear Bodies

    相似性Belongs to the MT-A70-like family.
    功能Probable methyltransferase.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料METTL4 is a 472 amino acid enzyme that belongs to the MT-A70-like family. Other members of this family have enzymatic activity that results in the transfer of a methyl group to and from DNA, RNA or amino acids. The gene encoding METTL4 maps to chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases, representing about 2.5% of total DNA in cells. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. Also, three chromosomal abnormalities result from meiotic nondisjunction events of chromosome 18: Monosomy 18p, Trisomy 18 (also known as Edwards syndrome) and Tetrasomy 18p.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Liver(Rat) Cell Lysate at 40 ug
    Primary: Anti-METTL4 (bs-18851R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 54 kD
    Observed band size: 54 kD
    产品细节图片2
    Sample:
    Lane 1: Mouse Heart tissue lysates
    Lane 2: Rat Cerebrum tissue lysates
    Primary: Anti-METTL4 (bs-18851R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 54 kDa
    Observed band size: 54 kDa

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    该产品被引用文献

    [IF={{ 5.9 }}] {Xuejing Sun. et al. Roseburia intestinalis Supplementation Could Reverse the Learning and Memory Impairment and m6A Methylation Modification Decrease Caused by 27-Hydroxycholesterol in Mice. NUTRIENTS. 2024 Jan;16(9):1288} {WB} {Mouse}

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    文献支持
    METTL4 Rabbit pAb(bs-18851R)-50ul/100ul/200ul
    ¥1180 - 2800