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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-18851R |
| 英文名称 | METTL4 Rabbit pAb |
| 中文名称 | 甲基化样蛋白4抗体 |
| 英文别名 | FLJ11350; methyltransferase like 2; Methyltransferase like 2B; Methyltransferase-like protein 2B; METL; METTL2; METTL2A; PSENIP1. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse, Rat (Human, Dog, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human METTL4 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 54 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > Methylated DNA Epigenetics and Nuclear Signaling > DNA methylation > DNMTs Epigenetics and Nuclear Signaling > DNA methylation > Methylated DNA Associated Tags & Cell Markers > Subcellular Markers > Nucleus > Other Nuclear Bodies |
| 相似性 | Belongs to the MT-A70-like family. |
| 功能 | Probable methyltransferase. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | METTL4 is a 472 amino acid enzyme that belongs to the MT-A70-like family. Other members of this family have enzymatic activity that results in the transfer of a methyl group to and from DNA, RNA or amino acids. The gene encoding METTL4 maps to chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases, representing about 2.5% of total DNA in cells. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. Also, three chromosomal abnormalities result from meiotic nondisjunction events of chromosome 18: Monosomy 18p, Trisomy 18 (also known as Edwards syndrome) and Tetrasomy 18p. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

_x000D_ Liver(Rat) Cell Lysate at 40 ug
_x000D_ Primary: Anti-METTL4 (bs-18851R) at 1/300 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 54 kD
_x000D_ Observed band size: 54 kD

_x000D_ Lane 1: Mouse Heart tissue lysates
_x000D_ Lane 2: Rat Cerebrum tissue lysates
_x000D_ Primary: Anti-METTL4 (bs-18851R) at 1/1000 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 54 kDa
_x000D_ Observed band size: 54 kDa
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