GRM6 | mGluR6 Rabbit pAb(bs-18802R)-50ul/100ul/200ul产品图

GRM6 | mGluR6 Rabbit pAb(bs-18

802R)-50ul/100ul/200ul
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  • ￥1180 - 2800
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  • bs-18802R
  • 2026年10月13日
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    北京博奥森生物技术有限公司
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      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-18802R
    英文名称mGluR6 Rabbit pAb
    中文名称促代谢型谷氨酸受体6抗体
    英文别名Metabotropic Glutamate Receptor 6; CSNB1B; DKFZp686H1993; GluR6; Glutamate receptor metabotropic 6; GPRC1F; GRM6; GRM6_HUMAN; Metabotropic glutamate receptor 6; mGlu6; mGluR6.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human mGluR6
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量33, 95 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Glutamate Receptors

    Neuroscience > Neurotransmitter > Amino Acids > Glutamate

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚基 Homodimer.
    亚细胞定位Cell membrane.
    组织特异性Detected in melanocytes.
    相似性Belongs to the G-protein coupled receptor 3 family.
    功能Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Feb 2012]

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {ICC/IF}{1:100-500}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

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    GRM6 | mGluR6 Rabbit pAb(bs-18802R)-50ul/100ul/200ul
    ￥1180 - 2800