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| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-18785R |
| 英文名称 | GPR50/Melatonin Related Receptor Rabbit pAb |
| 中文名称 | 褪黑激素相关受体抗体 |
| 英文别名 | G protein coupled receptor 50; G protein-coupled receptor 50; GPR 50; Gpr50; H9; Mel1c; Melatonin-related receptor; MGC125342; MTNRL; MTR1L_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Dog, Horse, Rabbit, Cat) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GPR50/Melatonin Related Receptor |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 67 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurology process > Metabolism Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Hypothalamus and pituitary. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Jurkat(Human) Cell Lysate at 30 ug
Primary: Anti-GPR50/Melatonin Related Receptor (bs-18785R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 67 kD
Observed band size: 63 kD
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文献和实验Characterization of CGRP Receptor Binding
Chatterjee, T.K. and Fisher, R.A. 1991. Multiple affinity forms of the calcitonin gene‐related peptide receptor in rat cerebellum. Mol. Pharmacol. 39:798‐804. Choksi, T
Overview of Receptor Allosterism
. Bruns, R.F. and Fergus, J.H. 1990. Allosteric enhancement of adenosine A1 receptor binding and function by 2‐amino‐3‐benzoylthiophenes. Mol. Pharmacol. 38:939‐949.
Bacterial Expression of Prolactin Family Proteins
Complementary DNAs of three recombinant proteins related to the prolactin family: ovine placental lactogen (oPL), ovine prolactin (oPRL), and rabbit soluble extracellular domain of prolactin receptor (rbPRLR-ECD) were subcloned by different
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