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产品信息以Bioss网站为准
- 规格:
50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-18551R |
| 英文名称 | ZCCHC24/C10orf56 Rabbit pAb |
| 中文名称 | 10号染色体开放阅读框56抗体 |
| 英文别名 | C10orf56; Chromosome 10 open reading frame 56; Zinc finger CCHC domain-containing protein 24; Zinc finger, CCHC domain containing 24. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Zebrafish, Danio) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ZCCHC24/C10orf56 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 27 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ZCCHC24 is a 241 amino acid protein that contains one CCHC-type zinc finger, suggesting a role in transcriptional regulation. The gene encoding ZCCHC24 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Primary: Anti-ZCCHC24/C10orf56 (bs-18551R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27 kD
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文献和实验Immunity:北大蒋争凡课题组发现 STING 后高尔基体囊泡转运的重要性及机制
)及维持 STING 激活所需要的脂膜环境(lipid environment),从而帮助 STING 更加稳定高效的激活。 本工作首先通过 CRISPR-Cas9 介导的全基因组筛选在 HeLa 细胞系中鉴定到一个未知功能的新基因 C10ORF76 (又名 ARMH3) 对 STING 的激活十分重要。ARMH3 是一个鲜少被研究的蛋白,为数不多的几篇文章暗示了它对于 PI4KB 发挥激酶活性来磷酸化磷脂酰肌醇(phosphatidylinositol,PI)生成 PI4P 十分重要。免疫
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
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