产品封面图

Timeless Recombinant Rabbit mA

b(bsm-54697R)-100ul/50ul
收藏
  • ￥1400 - 2500
  • Bioss已认证
  • bsm-54697R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
9 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 文献和实验
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      100ul/50ul

    规格：100ul产品价格：￥2500.0
    规格：50ul产品价格：￥1400.0
    产品编号bsm-54697R
    英文名称Timeless Recombinant Rabbit mAb
    中文名称恒定生物钟同源蛋白TIM1重组兔单克隆抗体
    英文别名FLJ12640; FLJ20714; hTIM; Protein timeless homolog; TIM; TIM_HUMAN; TIM1; Timeless; timeless circadian clock 1; timeless circadian clock; timeless homolog; TIMELESS1; Tof1 homolog.
    产品应用WB=1:500-2000, IHC-P=1:50-200, IHC-F=1:50-200, IF=1:50-200

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Human)
    抗体来源Rabbit
    免疫原Recombinant Human Timeless protein
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Recombinant
    理论分子量139 kDa
    浓度1mg/ml
    储存液1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300.
    研究领域

    Epigenetics and Nuclear Signaling > DNA / RNA > DNA Damage & Repair > DNA Damage Response > DNA Damage Recognition

    亚基Homodimer or homomultimer.
    亚细胞定位Nucleus.
    组织特异性Expressed in all tissues examined including brain, heart, lung, liver, skeletal muscle, kidney, placenta, pancreas, spleen, thymus and testis. Highest levels of expression in placenta, pancreas, thymus and testis.
    相似性Belongs to the timeless family.
    功能Required for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Promotes TIPIN nuclear localiZation. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders. [provided by RefSeq, Feb 2014]

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:50-200}
    {IHC-F}{1:50-200}
    {IF}{1:50-200}

     

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    相关实验
    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    Timeless Recombinant Rabbit mAb
    ￥850
    杭州戴格生物技术有限公司
    2025年05月18日询价
    Timeless Rabbit mAb[56574]
    询价
    南京赛戈巍生物科技有限公司
    2025年09月22日询价
    TIMELESS Rabbit mAb(Clone:22T48)
    ￥1990
    上海圻明生物科技有限公司
    2025年07月12日询价
    TIMELESS rabbit pAb
    询价
    ImmunoWay Biotechnology Company
    2025年07月08日询价
    TIMELESS Rabbit Polyclonal Antibody
    ￥500
    北京百奥创新科技有限公司
    2025年05月28日询价
    Timeless Recombinant Rabbit mAb(bsm-54697R)-100ul/50ul
    ￥1400 - 2500