Sample:
_x000D_
Kidney (Mouse) Lysate at 40 ug
_x000D_
Lung (Mouse) Lysate at 40 ug
_x000D_
Primary: Anti-IRX1 (bs-20469R) at 1/300 dilution
_x000D_
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_
Predicted band size: 50 kD
_x000D_
Observed band size: 50 kD
- ￥1180 - 2800
- Bioss
- bs-20469R
- 2026年10月13日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-20469R |
| 英文名称 | IRX1 Rabbit pAb |
| 中文名称 | Iroquois同源蛋白1抗体 |
| 英文别名 | Iroquois Homeobox Protein 1; Iroquois-class homeodomain protein IRX-1; IRXA1; IRX1_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Chicken, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human IRX1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 50 kDa |
| 浓度 | 1mg/ml |
| 储存液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > IRX/IRO Neuroscience > Neurology process > Neurogenesis |
| 亚细胞定位 | Nuclear |
| 相似性 | Belongs to the TALE/IRO homeobox family. Contains 1 homeobox DNA-binding domain._x000D_ |
| 功能 | IRX1 is a member of the Iroquois homeobox gene family. The genes from this family have multiple roles in vertebrate development. The gene encoding IRX1 is expressed in the brain, lung and gut during specific stages of mouse development. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The Iroquois homeobox gene family of transcription factors regulate aspects of embryonic development including anterior/posterior and dorsal/ventral axis patterning in the central nervous system. The Iroquois family are clustered on two loci, IRXA and IRXB, which map to chromosomes 8 and 13 in mice. The IRXA group includes Irx1, Irx2 and Irx4; the IRXB group is comprises Irx3, Irx5 and Irx6. Irx1 and Irx2 are both widely expressed during development in the lung epithelium and also in the ventricular septum. Irx1 and Irx2 also play a role in digit formation (E11.5–E14.5). The Irx gene family members are each expressed in a distinct pattern during mouse heart development. Specifically, Irx1 and Irx2 are expressed in the ventricular septum and Irx3 is expressed in the ventricular trabeculated myocardium. In addition, Irx4 is expressed in the linear heart tube and the AV canal; Irx5 is expressed in the endocardium lining the ventricular and atrial myocardium. Furthermore, the IRX4 gene may modulate cardiac development and function. Although the heart of Irx4(-) mice appears to develop normally, adult Irx4(-) mice exhibit cardiomyopathy, including cardiac hypertrophy and decreased contractility. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:Cerebrum (Mouse)Lysate at 40 ug
_x000D_ Primary: Anti-IRX1(bs-20469R)at 1/300 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
_x000D_ Predicted band size: 50kD
_x000D_ Observed band size: 50kD
_x000D_
_x000D_ Primary: Anti-IRX1(bs-20469R)at 1/300 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
_x000D_ Predicted band size: 50kD
_x000D_ Observed band size: 50kD
_x000D_
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IRX1 Rabbit pAb(bs-20469R)-50ul/100ul/200ul
￥1180 - 2800
