Sample:Bone (Mouse)Lysate at 40 ug
Primary: Anti-TGFBI(bs-7443R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 72kD
Observed band size: 72kD
- ￥1180 - 2800
- Bioss
- bs-7443R
- 2025年10月16日
- 产品信息以Bioss网站为准
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-7443R |
| 英文名称 | TGFBI Rabbit pAb |
| 中文名称 | 角膜上皮蛋白TGFBI抗体 |
| 英文别名 | AI181842; AI747162; beta ig; beta ig h3; beta ig-h3; BGH3_HUMAN; Big h3; BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; Kerato epithelin; Kerato-epithelin; LCD1. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse, Rat (Human, Dog, Pig, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TGFBI |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 72 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Developmental Biology > Organogenesis > Excretory system development > Kidney development Neuroscience > Sensory System > Visual system Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Collagen Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Other ECM Proteins Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone Signal Transduction > Growth Factors/Hormones > TGF |
| 亚细胞定位 | Secreted > extracellular space > extracellular matrix. May be associated both with microfibrils and with the cell surface. Tissue Specificity : Highly expressed in the corneal epithelium. |
| 组织特异性 | Highly expressed in the corneal epithelium. |
| 翻译后修饰 | Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. |
| 相似性 | Contains 1 EMI domain. Contains 4 FAS1 domains. |
| 功能 | Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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[IF={{ 14.511 }}] {Ying Xia. et al. SB431542 alleviates lupus nephritis by regulating B cells and inhibiting the TLR9/TGFβ1/PDGFB signaling. J AUTOIMMUN. 2022 Oct;132:102894} {IHC} {Mouse}
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TGFBI Rabbit pAb(bs-7443R)-50ul/100ul/200ul
￥1180 - 2800
