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- 2025年10月16日
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| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-16250R |
| 英文名称 | GLOD4 Rabbit pAb |
| 中文名称 | GLOD4蛋白抗体 |
| 英文别名 | C17orf25; CGI 150; Glod4; GLOD4_HUMAN; Glyoxalase domain containing 4; glyoxalase domain containing protein 4; Glyoxalase domain-containing protein 4; HC71; my027. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Dog, Pig, Cow, Horse, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GLOD4 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 35 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Signal Transduction > Metabolism > Energy Metabolism |
| 亚细胞定位 | Mitochondrion. |
| 组织特异性 | Expressed in heart, brain, liver, kidney, pancreas and placenta. Not expressed in skeletal muscle and lung. |
| 相似性 | Belongs to the glyoxalase I family. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GLOD4 is a 313 amino acid protein belonging to the glyoxalase I family. GLOD4 interacts with NUDT9, a highly specific adenosine diphosphate ribose pyrophosphatase. Localized to mitochondrion, GLOD4 is expressed in heart, brain, liver, kidney, pancreas and placenta, but is not found in skeletal muscle or lung. Expression of GLOD4 is decreased in hepatocellular carcinoma samples in comparison to adjacent non-cancerous liver tissues from the same patients. Transfection of GLOD4 in hepatocellular carcinoma cells and overexpression has also been shown to inhibit cell growth. GLOD4 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 17p13.3. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验[IF={{ 3.331 }}] {Wang X et al. Characterization of GLOD4 in Leydig Cells of Tibetan Sheep During Different Stages of Maturity. Genes (Basel). 2019 Oct 12;10(10). pii: E796.} {WB,IHC,IF} {sheep}
[IF={{ 2.7 }}] {Jinqian Wang. et al. Expression of GLOD4 in the Testis of the Qianbei Ma Goat and Its Effect on Leydig Cells. ANIMALS. 2024 Jan;14(17):2611} {WB,IHC} {Goat}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
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