- ￥1180 - 2800
- Bioss
- bs-16100R
- 2025年10月16日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
Integrin Alpha 3 + Beta 1 Rabbit pAb, BF405 conjugated(bs-1057R-BF405)-100ul
￥2980HLA-C Mouse mAb, HRP conjugated(bsm-43093M-HRP)-100ul
￥2980Gbx1 Rabbit pAb, PE-Cy5 conjugated(bs-11660R-PE-Cy5)-100ul
￥2980
TRMT2B Rabbit pAb(bs-16104R)-50ul/100ul/200ul
￥1180CD73 Rabbit pAb, PE-Cy5 conjugated(bs-4834R-PE-Cy5)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-16100R |
| 英文名称 | FLG2 Rabbit pAb |
| 中文名称 | FLG2蛋白抗体 |
| 英文别名 | FILA2_HUMAN; Filaggrin-2; FLG-2; FLG2; Ifapsoriasin; Intermediate filament-associated and psoriasis-susceptibility protein. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human FLG2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 248 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Binding Proteins |
| 相似性 | Belongs to the S100-fused protein family. In the N-terminal section; belongs to the S-100 family. Contains 2 EF-hand domains. Contains 10 filaggrin repeats. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Profilaggrin is a large, insoluble, highly phosphorylated precursor protein and major component of keratohyalin granules in the living cells of the epidermis. During terminal differentiation of the epidermis, profilaggrin is proteolytically processed into active Filaggrin molecules that promote aggregation and disulfide-bond formation of keratin intermediate filaments. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that Filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery. Filaggrin 2, also known as FLG2, Ifapsoriasin or IFPS (intermediate filament-associated and psoriasis-susceptibility protein), is a 2,391 amino acid protein that shares common structural features with Filaggrin. Filaggrin 2 contains ten Filaggrin repeats, two EF-hand domains and belongs to both the S-100 and S100-fused protein families. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验[IF={{ 2.7 }}] {Yi Zhong. et al. GSDMD suppresses keratinocyte differentiation by inhibiting FLG expression and attenuating KCTD6-mediated HDAC1 degradation in atopic dermatitis. PEERJ. 2024 Jan;12:e16768} {WB} {Human}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
技术资料暂无技术资料 索取技术资料
