Sample:
_x000D_
B16(Mouse) Cell Lysate at 40 ug
_x000D_
Primary: Anti-FcRH2 (bs-16065R) at 1/300 dilution
_x000D_
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_
Predicted band size: 53 kD
_x000D_
Observed band size: 53 kD
- ￥1180 - 2800
- Bioss
- bs-16065R
- 2026年10月13日
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- 文献和实验
- 技术资料
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-16065R |
| 英文名称 | FcRH2 Rabbit pAb |
| 中文名称 | CD307b抗体 |
| 英文别名 | CD307b; Fc receptor homolog 2; Fc receptor like protein 2; Fc receptor-like protein 2; FcR-like protein 2; FcRH2; FCRL 2; FcRL2; FCRL2_HUMAN; IFGP family protein 4; IFGP4; Immunoglobulin receptor translocation associated 4 protein; Immunoglobulin receptor translocation-associated protein 4; IRTA4; SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1; SPAP1. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human FcRH2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 53 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Adaptive Immunity > B Cells > Non-CD Immunology > Immunoglobulins > Receptors |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B-cell lines. Preferentially expressed in memory B-cells (at protein level). |
| 翻译后修饰 | Isoform 2 is N- and O-glycosylated, and phosphorylated. |
| 相似性 | Contains 4 Ig-like C2-type (immunoglobulin-like) domains. |
| 功能 | May have an regulatory role in normal and neoplastic B cell development. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The Fc receptor homolog (FcRH) family of proteins are related to the classical Fc receptors (FcR) and belong to the immunoglobulin receptor superfamily. The proteins in the FcRH family are type I transmembrane glycoproteins and consist of FcRH1-FcRH6. The genes encoding the human FcRH proteins map to chromosome 1, near the related FCR genes. The FcRH proteins, which are involved in immune system regulation, have immunoreceptor-tyrosine inhibitory motifs in their cytoplasmic domains. Mutations in the gene encoding for the FcRH proteins may be associated with systemic lupus erythematosus, autoimmune thyroid disease and rheumatoid arthritis. The FcRH genes are expressed primarily, although not exclusively, by mature B lineage cells, and may serve important regulatory roles in normal and neoplastic B cell development. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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FCRL2 | FcRH2/CD307b Rabbit pAb(bs-16065R)-50ul/100ul/200ul
￥1180 - 2800
