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RERG Rabbit pAb(bs-6091R)-50ul

/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-6091R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-6091R
    英文名称RERG Rabbit pAb
    中文名称Ras相关雌激素调节生长抑制蛋白抗体
    英文别名RAS like estrogen regulated growth inhibitor; Ras related and estrogen regulated growth inhibitor; Ras-related and estrogen-regulated growth inhibitor; Rerg; RERG_HUMAN; Weakly similar to N ras protein.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse, Rat (Human, Chicken, Dog, Cow, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human RERG
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量22 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Oncoproteins/suppressors > Tumor suppressors

    Cancer > Signal transduction > G protein signaling > Small G proteins > Ras family

    Signal Transduction > Growth Factors/Hormones > Hormones

    Signal Transduction > Second Messenger > Nucleotide Messenger > GTP

    Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Ras Family

    亚细胞定位 Cytoplasm.
    组织特异性Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of primary breast tumors with poor clinical prognosis.
    相似性Belongs to the small GTPase superfamily. Ras family.
    功能Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    Sample:
    Lung (Mouse) Lysate at 40 ug
    Primary: Anti- RERG (bs-6091R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 22 kD
    Observed band size: 25 kD
    产品细节图片2
    P‌‌araformaldehyde-fixed, paraffin embedded (rat skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RERG) Polyclonal Antibody, Unconjugated (bs-6091R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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    RERG Rabbit pAb(bs-6091R)-50ul/100ul/200ul
    ¥1180 - 2800