Tissue/cell: human laryngeal tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-MDP1 / DNA Polymerase gamma Polyclonal Antibody, Unconjugated(bs-13017R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
- ￥1180 - 2800
- Bioss
- bs-13017R
- 2025年10月16日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
Ku70 / XRCC6 Rabbit pAb, Cy5.5 conjugated(bs-2295R-Cy5.5)-100ul
￥2980Aldolase A Rabbit pAb, PerCP-Cy7 conjugated(bs-2406R-PerCP-Cy7)-100ul
￥2980CYP2E1 Rabbit pAb, BF405 conjugated(bs-4562R-BF405)-100ul
￥2980
CRIPTO Mouse mAb(bsm-2313M)-50ul/100ul/200ul/200ug
￥1180ITM2A Rabbit pAb, BF680 conjugated(bs-9705R-BF680)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-13017R |
| 英文名称 | POLG Rabbit pAb |
| 中文名称 | DNA聚合酶γ/DNA pol γ抗体 |
| 英文别名 | DNA directed DNA polymerase gamma; DNA polymerase subunit gamma 1; DNA polymerase subunit gamma-1; DPOG1_HUMAN; Mitochondrial DNA polymerase catalytic subunit; Mitochondrial DNA polymerase gamma; POLG 1; POLG A; PolG alpha; PolG-alpha; Polymerase(DNA directed) gamma; PEO; MDP1; SCAE; MIRAS; ORF-Y; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B; POLGARF; |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Pig) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human POLG |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 140 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > DNA Synthesis > DNA Polymerases Metabolism > Pathways and Processes > Metabolic signaling pathways > Nucleotide metabolism > Molecular processes > Mitochondrial transcription Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial Biogenesis |
| 亚基 | Heterotrimer composed of a catalytic subunit and a homodimer of accessory subunits. |
| 亚细胞定位 | Mitochondrion. |
| 相似性 | Belongs to the DNA polymerase type-A family. |
| 功能 | Involved in the replication of mitochondrial DNA. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases (DNA pol). DNA pol Alpha, Beta, Gamma, and epsilon are involved in DNA replication and repair. DNA pol gamma and DNA pol e are multi-subunit enzymes, with DNA pol gamma consisting of two subunits: p125, which interacts with the sliding DNA clamp protein, PCNA, and p50. The nuclear-encoded DNA pol Delta is the only DNA polymerase required for the replication of the mitochondrial DNA. DNA pol zeta is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis. DNA pol theta is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
Tissue/cell: human colon cancer; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-MDP1 / DNA Polymerase gamma Polyclonal Antibody, Unconjugated(bs-13017R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-MDP1 / DNA Polymerase gamma Polyclonal Antibody, Unconjugated(bs-13017R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
[IF={{ 6.24 }}] {Chen, Xubo, et al. "The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways." Redox Biology (2017).} {WB} {="Rat"}
[IF={{ 5.8 }}] {Fei Zheng. et al.Mung bean-derived carbon dots suppress ferroptosis of Schwann cellsviathe Nrf2/HO-1/GPX4 pathway to promote peripheral nerve repair†.BIOMATERIALS SCIENCE.2025 Jan 27.} {Western blot} {mouse}
技术资料暂无技术资料 索取技术资料
文献支持
POLG Rabbit pAb(bs-13017R)-50ul/100ul/200ul
￥1180 - 2800
