Sample:
_x000D_
Lane 1: Mouse Hippocampus tissue lysates
_x000D_
Lane 2: Mouse Cerebral cortex tissue lysates
_x000D_
Primary: Anti-PCDH11X (bs-11107R) at 1/1000 dilution
_x000D_
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_
Predicted band size: 145 kDa
_x000D_
Observed band size: 110 kDa
- ￥1180 - 2800
- Bioss
- bs-11107R
- 2026年10月13日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-11107R |
| 英文名称 | PCDH11X Rabbit pAb |
| 中文名称 | 原钙粘附蛋白11X抗体 |
| 英文别名 | PCDH11; PCDH22; PCDHX; PCDHY; Protocadherin 11; Protocadherin 11 X linked; Protocadherin 11 Y linked; Protocadherin 22; Protocadherin on the X chromosome; Protocadherin on the Y chromosome; Protocadherin PC; Protocadherin prostate cancer; PC11X_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse (Rat, Pig, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PCDH11X |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 145 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Cell Adhesion Proteins > Membrane Proteins Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cadherins |
| 亚基 | Interacts with CTNNB1. |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed strongly in fetal brain and brain (cortex, amygdala, thalamus, substantia nigra, hippocampus, caudate nucleus and corpus callosum). Expressed at low level in testis. Expressed in apoptosis-resistant cells. |
| 相似性 | Contains 7 cadherin domains. _x000D_ |
| 功能 | PCDH11Y (Protocadherin 11 Y-linked) is a member of the protocadherin family. Protocadherins constitute the largest subgroup within the cadherin family of calcium-dependent cell-cell adhesion molecules. Their specific functions are unknown but they may be involved in the establishment and function of specific neuronal connections in the brain. The PCDH11Y gene is located in a major X/Y block of homology and its most closely related cadherin superfamily member is located in this homologous region on the X chromosome (PCDH11X). |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Transcripts arising from alternative splicing encode isoforms with variable cytoplasmic domains. [provided by RefSeq, Jul 2008]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
_x000D_ Lane 1: Human SH-SY5Y cell lysates
_x000D_ Lane 2: Human U251 cell lysates
_x000D_ Lane 3: Human U87MG cell lysates
_x000D_ Primary: Anti- PCDH11X (bs-11107R) at 1/1000 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 145 kDa
_x000D_ Observed band size: 120 kDa
_x000D_ _x000D_
_x000D_ Lane 1: Human SH-SY5Y cell lysates
_x000D_ Lane 2: Human U251 cell lysates
_x000D_ Lane 3: Human U87MG cell lysates
_x000D_ Primary: Anti- PCDH11X (bs-11107R) at 1/1000 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 145 kDa
_x000D_ Observed band size: 120 kDa
_x000D_ _x000D_
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PCDH11X | PCDH-X Rabbit pAb(bs-11107R)-50ul/100ul/200ul
￥1180 - 2800
