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- Bioss
- bs-18731R
- 2026年10月13日
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- 技术资料
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-18731R |
| 英文名称 | mucolipin 1 Rabbit pAb |
| 中文名称 | 粘脂蛋白1抗体 |
| 英文别名 | MCLN1_HUMAN; Mcoln 1; Mcoln1; MG 2; MG-2; MG2; ML 4; ML4; MLIV; MST080; MSTP080; Mucolipidin; Mucolipin-1; Mucolipin1; TRP ML1; TRPML1. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, Monkey, Cat) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human mucolipin 1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 65 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Signaling Pathway > Calcium Signaling |
| 亚细胞定位 | Cell membrane. Late endosome membrane. Lysosome membrane.Entrez Gene: 57192 Human_x000D_ Entrez Gene: 94178 Mouse_x000D_ Entrez Gene: 288371 Rat_x000D_ Omim: 605248 Human_x000D_ SwissProt: Q9GZU1 Human_x000D_ SwissProt: Q99J21 Mouse_x000D_ Unigene: 567548 Human_x000D_ Unigene: 631858 Human_x000D_ Unigene: 8356 Mouse |
| 组织特异性 | Widely expressed in adult and fetal tissues. |
| 相似性 | Belongs to the transient receptor (TC 1.A.4) family. Polycystin subfamily. MCOLN1 sub-subfamily. |
| 功能 | Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV. [provided by RefSeq, Oct 2009] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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MCOLN1 | TRPML1/ML1 Rabbit pAb(bs-18731R)-50ul/100ul/200ul
￥1180 - 2800
