mucolipin 1 Rabbit pAb(bs-18731R)-50ul/100ul/200ul

mucolipin 1 Rabbit pAb(bs-1873

1R)-50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-18731R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-18731R
    英文名称mucolipin 1 Rabbit pAb
    中文名称粘脂蛋白1抗体
    英文别名MCLN1_HUMAN; Mcoln 1; Mcoln1; MG 2; MG-2; MG2; ML 4; ML4; MLIV; MST080; MSTP080; Mucolipidin; Mucolipin-1; Mucolipin1; TRP ML1; TRPML1.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, Monkey, Cat)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human mucolipin 1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量65 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Signaling Pathway > Calcium Signaling

    亚细胞定位Cell membrane. Late endosome membrane. Lysosome membrane.Entrez Gene: 57192 Human Entrez Gene: 94178 Mouse Entrez Gene: 288371 Rat Omim: 605248 Human SwissProt: Q9GZU1 Human SwissProt: Q99J21 Mouse Unigene: 567548 Human Unigene: 631858 Human Unigene: 8356 Mouse
    组织特异性Widely expressed in adult and fetal tissues.
    相似性Belongs to the transient receptor (TC 1.A.4) family. Polycystin subfamily. MCOLN1 sub-subfamily.
    功能Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV. [provided by RefSeq, Oct 2009]

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {ICC/IF}{1:100-500}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

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