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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-17135R |
| 英文名称 | SOX18 Rabbit pAb |
| 中文名称 | 转录因子SOX18抗体 |
| 英文别名 | HLTS; SOX 18; Sox18; SOX18_HUMAN; SRY(sex determining region Y) box 18; SRY box 18; Transcription factor SOX 18; Transcription factor SOX-18. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Dog, Pig, Cow, Rhesus monkey) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SOX18 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 41 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Other factors Epigenetics and Nuclear Signaling > Transcription > Transcription Factors |
| 亚细胞定位 | Nucleus. |
| 相似性 | Contains 1 HMG box DNA-binding domain. Contains 1 Sox C-terminal domain. |
| 功能 | Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Primary: rabbit Anti-SOX18 (bs-17135R) at 1:300;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000;
Predicted band size: 41 kD
Observed band size: 41 kD
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文献和实验[IF={{ 7.5 }}] {Ying Feng. et al. The SOX18-OTUB1-YAP1 axis: a new endometriosis target. J TRANSL MED. 2025 Jun;23:647} {IHC} {Human}
[IF={{ 5.6 }}] {Mingliang He. et al. SOX18 Promotes the Proliferation of Dermal Papilla Cells via the Wnt/β-Catenin Signaling Pathway. INT J MOL SCI. 2023 Jan;24(23):16672} {IF} {Sheep}
[IF={{ 3 }}] {Xiaoyang Lv. et al. SP1 and KROX20 Regulate the Proliferation of Dermal Papilla Cells and Target the CUX1 Gene. ANIMALS. 2024 Jan;14(3):429} {IF} {Sheep}
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