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S100A11 Rabbit pAb(bs-10310R)-

50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-10310R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-10310R
    英文名称S100A11 Rabbit pAb
    中文名称S100钙结合蛋白A11抗体
    英文别名S10AB_HUMAN; Protein S100-A11; Calgizzarin; Metastatic lymph node gene 70 protein(MLN 70); Protein S100-C; S100 calcium-binding protein A11; S100 calcium binding protein A11; MLN70; S100C; HEL-S-43;
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human S100A11
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量13 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Cell Cycle > Cell Cycle Inhibitors

    Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Binding Proteins

    亚基Homodimer; disulfide-linked.
    亚细胞定位Cytoplasm. Nucleus.
    翻译后修饰Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation.
    相似性Belongs to the S-100 family.
    Contains 2 EF-hand domains.
    功能Facilitates the differentiation and the cornification of keratinocytes.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq]

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {ICC/IF}{1:100-500}
    {IF}{1:100-500}

     

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