ZBTB46 | BZEL/ZNF340 Rabbit pAb(bs-13579R)-50ul/100ul/200ul产品图

ZBTB46 | BZEL/ZNF340 Rabbit pA

b(bs-13579R)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-13579R
  • 2026年10月13日
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    • 规格:

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-13579R
    英文名称ZBTB46 Rabbit pAb
    中文名称锌指蛋白340抗体
    英文别名BTB/POZ domain containing protein 4; BTBD4; RINZF; Zinc finger and BTB domain containing 46; Zinc finger and BTB domain containing protein 46; Zinc finger protein 340; ZNF340; ZBT46_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Chicken, Horse, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ZBTB46
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量64 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger

    组织特异性Nucleus (Potential).
    翻译后修饰Sumoylated. Desumoylation by PPPDE2 reverses transcriptional repression activity (By similarity). _x000D_
    相似性Contains 1 BTB (POZ) domain.
    Contains 2 C2H2-type zinc fingers. _x000D_
    功能ZBTB46 may be involved in transcriptional regulation. It contains one BTB (POZ) domain and two C2H2 type zinc fingers.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    _x000D_ Liver (Mouse) Lysate at 40 ug
    _x000D_ Primary: Anti-ZBTB46 (bs-13579R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 64 kD
    _x000D_ Observed band size: 64 kD

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    ZBTB46 | BZEL/ZNF340 Rabbit pAb(bs-13579R)-50ul/100ul/200ul
    ¥1180 - 2800