β-Catenin Mouse Monoclonal Ant

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The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development

Product Name:β-Catenin Mouse Monoclonal Antibody

Isotype: IgG1

Storage Buffer :PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol

Storage instructions:-20°C. Do not aliquot the antibody

Recommended dilutions: WB: 1:1,000-2,000 IHC: 1:200-500

Optimal dilutions should be determined by the end user.

Specificity:The β-Catenin Mouse Monoclonal antibody detects endogenous β-Catenin proteins.

Alternative Names: beta catenin, b-catenin, CTNB1, CTNNB1, FLJ25606, OTTHUMP00000162082

Form: Liquid

Reactivity:H, R, M

Molecular Weight:~92KD

Western blot analysis of 1) Hela, 2) 293T, 3)Mouse Liver Tissue, 4) Rat Liver Tissue, with β-Catenin Mouse mAb BE3365 diluted at 1:2,000.

Immunohistochemical analysis of paraffin-embedded Human Lung caricnoma using β-Catenin （BE3365）Mouse mAb diluted at 1:500.