CA IX/Carbonic Anhydrase IX Mo

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The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors.

Product Name:CA IX/Carbonic Anhydrase IX Mouse Monoclonal Antibody

Clone Number: 11F9

Isotype: IgG1

Storage Buffer :PBS, pH 7.4, containing 0.02% sodium azideas Preservative and 50% Glycerol

Storage instructions:-20°C. Do not aliquot the antibody

Recommended dilutions: WB: 1:3,000 IP: 1:200

Optimal dilutions should be determined by the end user.

Specificity: CA IX Mouse Monoclonal antibody detects endogenous CA IX proteins.

Molecular Weight:35-58KD

Form: Liquid

Reactivity:H

Western blot analysis of 1) Hela, 2) 293T, with CA IX Mouse mAb diluted at 1:5,000.

1、Input: Hela Cell Lysate

2、IP product: IP dilute 1:200

Western blot analysis:primary antibody:BE31091:2,000

Secondary antibody: Goat anti-Mouse IgG,Light chain specific(BE0105),1:5,000