COX1/Cyclooxygenase 1 Rabbit

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Cyclooxygenase-1 (COX-1), also known as prostaglandin G/H synthase 1, prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1, is an enzyme that in humans is encoded by the PTGS1 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.

Product Name:COX1/Cyclooxygenase 1 Rabbit Polyclonal Antibody

Isotype: IgG1

Storage Buffer :PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol

Storage instructions:-20°C. Do not aliquot the antibody

Recommended dilutions: WB: 1:1,000 IHC: 1:100

Optimal dilutions should be determined by the end user.

Specificity: The COX1 Rabbit Polyclonal antibody detects endogenous COX1 proteins.

Molecular Weight:70KD

Form: Liquid

Reactivity:H

Western blot analysis of Hela with COX1 Rabbit Polyclonal antibody diluted at 1:1,000