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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C
- 保质期:
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -2027℃ for several months.
- 英文名:
Fedratinib (SAR302503, TG101348)
- 库存:
详询
- 供应商:
详询
- CAS号:
936091-26-8
- 规格:
5mg/10mg/50mg/100mg/1ml/10mM
| 规格: | 5mg | 产品价格: | ¥851.0 |
|---|---|---|---|
| 规格: | 10mg | 产品价格: | ¥1168.0 |
| 规格: | 50mg | 产品价格: | ¥3900.0 |
| 规格: | 100mg | 产品价格: | ¥5735.0 |
| 规格: | 1ml/10mM | 产品价格: | ¥847.0 |
ID:T1995
PURITY:0.98
Formula:C27H36N6O3S
MolWt:524.68
Appearance:白色粉末
Solubility:G4100 mM in DMSO
Bioactivity:Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Phase 2.
Status:
Pathways:Tyrosine Kinase/Adaptors; JAK/STAT Signaling
Target:JAK inhibitor; FLT3 inhibitor; RET inhibitor
Receptor:JAK2/FLT3/RET
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文献和实验Transgenic Mouse and Gene Targeting Facility Tg 008 Southern Blotting Materials and Equipment Hybaid hybridization oven (ISC BioExpress,H-9250) Vacuum oven (VWR,52201-218) Ludlum Geiger Counter Radiation Shields and lock box (from various
Transgenic Mouse and Gene Targeting Facility Tg 008 Southern Blotting Materials and Equipment Hybaid hybridization oven (ISC BioExpress, H-9250) Vacuum oven (VWR, 52201-218) Ludlum Geiger Counter Radiation Shields
APP-Based Transgenic Models: The Tg2576 Model
, economic, and personal impact. In 1996, Karen Hsiao and colleagues showed that transgenic mice, which overexpress a human APP cDNA transgene from a Swedish family whose members showed early onset, familial AD (Tg2576 mice) were cognitively impaired
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