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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C
- 保质期:
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -1933℃ for several months.
- 英文名:
TG003
- 库存:
详询
- 供应商:
详询
- CAS号:
300801-52-9
- 规格:
5mg/10mg/25mg/50mg/1ml/10mM
| 规格: | 5mg | 产品价格: | ¥756.0 |
|---|---|---|---|
| 规格: | 10mg | 产品价格: | ¥1413.0 |
| 规格: | 25mg | 产品价格: | ¥2626.0 |
| 规格: | 50mg | 产品价格: | ¥4242.0 |
| 规格: | 1ml/10mM | 产品价格: | ¥752.0 |
ID:T1901
PURITY:0.98
Formula:C13H15NO2S
MolWt:249.33
Appearance:类白色粉末
Solubility:G4DMSO > 10 mM
Bioactivity:TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor with IC50 of 20 nM, 200 nM, and 15 nM for Clk1, Clk2, and Clk4, respectively. No inhibitory effect on Clk3, SRPK1, SRPK2, or PKC.
Status:
Pathways:Cell Cycle/Checkpoint
Target:CDK inhibitor
Receptor:CLK1/2/4
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文献和实验Transgenic Mouse and Gene Targeting Facility Tg 008 Southern Blotting Materials and Equipment Hybaid hybridization oven (ISC BioExpress,H-9250) Vacuum oven (VWR,52201-218) Ludlum Geiger Counter Radiation Shields and lock box (from various
Transgenic Mouse and Gene Targeting Facility Tg 008 Southern Blotting Materials and Equipment Hybaid hybridization oven (ISC BioExpress, H-9250) Vacuum oven (VWR, 52201-218) Ludlum Geiger Counter Radiation Shields
APP-Based Transgenic Models: The Tg2576 Model
, economic, and personal impact. In 1996, Karen Hsiao and colleagues showed that transgenic mice, which overexpress a human APP cDNA transgene from a Swedish family whose members showed early onset, familial AD (Tg2576 mice) were cognitively impaired
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