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- EKU06676
- 2025年07月13日
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文献和实验is almost catalytic when compared to antisense silencing. Of these targets, the uPAR-uPA system and MMPs holds great promise. Targeting uPA/uPAR may provide additive or synergistic treatment benefits if used in combination with conventional therapeutics
RFLP Molecular Analysis of the Urokinase-Type Plasminogen Activator Gene
proenzyme forms of matrix metalloproteases. Thus, uPA is a central molecule in pericellular proteolysis (1 -1 ). uPA (as well as other factors of the plasminogen activator system, the cell surface-associated uPA receptor [uPAR], and the plasminogen
Dissecting the Urokinase Activation Pathway Using Urokinase-Activated Anthrax Toxin
sequence of PrAg with other protease substrate sequences. PrAg-U2 is such a PrAg variant, one that is selectively activated by urokinase plasminogen activator (uPA). The uPA-dependent proteolytic activation of PrAg-U2 on the cell surface is readily detected
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