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文献和实验Purification of the Eucaryotic Heat-Shock Proteins Hsp70 and gp96
Heat-shock proteins (HSPs), highly conserved across species, are generally considered as intracellular proteins that have protective functions in situations of cellular stress. A wide variety of stressful stimuli like heat shock, ultraviolet
Preparation of a Heat-Shock Protein 70-Based Vaccine from DCTumor Fusion Cells
We have developed an enhanced molecular chaperone-based vaccine through rapid isolation of heat-shock protein 70 peptide complexes (Hsp70.PC) after the fusion of tumor and dendritic cells (DCs) (Hsp70.PC-F). In this approach, the tumor
Hsp70: Anti-apoptotic and Tumorigenic Protein
Heat shock protein 70 (Hsp70) is a powerful chaperone whose expression is induced in response to a wide variety of physiological and environmental insults, including anticancer chemotherapy, thus allowing the cell to survive to lethal
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