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- 2025年07月13日
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文献和实验reporter plasmids (TCF reporter plasmid kit; Upstate) is needed. B Pharmacological inhibition ofGSK-3 activity. MiaPaCa2 pancreatic cancer cells do not express E-cadherin and there is free (free from binding to Ecadherin)cytosolic β-catenin pool
fi eld. In the past decades, genome editing tools based onsequence-specifi c nucleases and DNA-binding proteins such aszinc-fi nger nucleases (ZFNs) [ 1 – 4 ], meganucleases [ 5 ], and transcriptionactivator like effectors (TALEs) [ 6 – 11
. Figure 2. The family of ABC transporters is characterized by the presence of an ATP-binding cassette region, which hydrolyzes ATP to support energy- dependent substrate exportation from the intracellular cytoplasm to the extracellular space
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