Biaffin ELK-1 ELK-1 (PEP-ELK1

JNK信号转导通路

稳定性和半衰期的调节。c―jun73位丝氨酸经JNK磷酸化后可有效地免受泛素化作用，导致c―jun半衰期延长。在非应激细胞中，JNK有促进靶基因产物泛素化的作用，这种作用取决于JNK与c―jun紧密结合的能力，而不是激酶活性。JNK调节c―jun的泛素化依赖于JNK与c―jun的相互结合作用以及c―jun的磷酸化水平。除c―jun是JNKMAPK的底物外，JNKMAPK也可磷酸化并激活其他转录因子。激活的JNK可使AP―1复合体中的其他组分蛋白发生磷酸化，包括junB、junD、ATF2和Elk

Exposure to, and Inactivation of, the Unconventional Agents that Cause Transmissible Degenerative Encephalopathies

are bovine spongiform encephalopathy (BSE), chronic wasting disease of elk and mule-deer, feline spongiform encephalopathy (FSE) of the domestic cat, scrapie in sheep and goats, and transmissible mink encephalopathy (TME). A number of exotic ruminant

Sex-Sorting Sperm Using Flow Cytometry/Cell Sorting

while maintaining; a purity of 90% such that it has been applied to cattle on a commercial basis. The sex of offspring has been predetermined in a wide variety of mammalian species including cattle, swine, horses, sheep, goats, dogs, cats, deer, elk, dolphins, water