Tight Junctions PCR Array 紧密连接

紧密连接基因表达PCR芯片可用于研究84个关键基因的表达。紧密连接基因编码的蛋白使上皮细胞之间形成疏水屏障来调节细胞极性、增殖和分化。通过实时定量PCR的方法，研究者即能够利用该芯片简单可靠地同时检测紧密连接相关基因的表达。
Cell Surface Receptors Claudins: CLDN1, CLDN10, CLDN11, CLDN12, CLDN14, CLDN15, CLDN16, CLDN17, CLDN18, CLDN19, CLDN2, CLDN3, CLDN4, CLDN5, CLDN6, CLDN7, CLDN8, CLDN9. Occludin: OCLN.
Cell Adhesion Molecules: ESAM, ICAM1, ICAM2, PECAM1.
Junctional Adhesion Molecules: F11R, IGSF5, JAM2, JAM3.
Others: CD99, CRB1, CRB3.
Alpha Actinins & Catenins: ACTN1, ACTN2, ACTN3, ACTN4, CTNNA1, CTNNA2, CTNNA3, CTNNB1.
Junction Interacting Proteins: ACTN1, ACTN2, ACTN3, ACTN4, AMOTL1, CGN, CSDA, CTTN, EPB41, HCLS1, INADL, MAGI1, MAGI2, MLLT4, MPDZ, PARD3, SYMPK, TJAP1, TJP1, TJP2, TJP3, VAPA, ZAK.
Cytoskeleton Regulators: AMOTL1, ASH1L, CSDA, CTTN, LLGL1, LLGL2, PARD3, PARD6A, PARD6B, SPTA1, SPTAN1, SPTB, SMURF1, TIAM1.
G Protein Signaling: ARHGEF2, CDC42, CDK4, GNAI1, RAC1, RHOA, SMURF1, TIAM1.
Protein Kinase Signaling: CASK, CSNK2A1, CSNK2A2, CSNK2B, ILK, MAGI1, MAGI2, MARK2, MPP5, MPP6, PRKCI, PRKCZ, PTEN.