Autophagy PCR Array 自噬基因表达PCR芯

自噬基因表达PCR芯片可用于研究参与自噬反应的84个关键基因的表达。该芯片包含了与细胞内外信号通路有关的自噬的分子基因，及其关键调控因子基因。利用该芯片研究者即能够利用该芯片简单可靠地同时检测自噬相关基因的表达。
Autophagy Machinery Components: Genes Involved in Autophagic Vacuole Formation: AMBRA1 (NYW1), ATG12, ATG16L1, ATG4A, ATG4B, ATG4C, ATG4D, ATG5, ATG9A, ATG9B, BECN1, GABARAP, GABARAPL1, GABARAPL2, IRGM, MAP1LC3A, MAP1LC3B, RGS19, ULK1, WIPI1.
Genes Responsible for Protein Targeting to Membrane / Vacuole: ATG4A, ATG4B, ATG4C, ATG4D, GABARAP.
Genes Responsible for Protein Transport: ATG10, ATG16L1, ATG16L2, ATG3, ATG4A, ATG4B, ATG4C, ATG4D, ATG7, ATG9A, GABARAP, GABARAPL2, RAB24.
Genes Linking Autophagosome to Lysosome: DRAM1, GABARAP, LAMP1, NPC1.
Genes Involved in Protein Ubiquitination: ATG3, ATG7, HDAC6.
Genes with Protease Activity: ATG4A, ATG4B, ATG4C, ATG4D.
Regulation of Autophagy: Co- Regulators of Autophagy and Apoptosis: AKT1, APP, ATG12, ATG5, BAD, BAK1, BAX, BCL2, BCL2L1 (BCL-X), BECN1, BID, BNIP3, CASP3, CASP8 (FLICE), CDKN1B (p27KIP1), CDKN2A (p16INK4), CLN3, CTSB, CXCR4, DAPK1, DRAM1, EIF2AK3, FADD, FAS (TNFRSF6), HDAC1, HTT, IFNG, IGF1, INS, MAPK8 (JNK1), MTOR, NFKB1, PIK3CG, PRKAA1, PTEN, SNCA, SQSTM1, TGFB1, TGM2, TNF, TNFSF10 (TRAIL), TP53.
Co-Regulators of Autophagy and the Cell Cycle: BAX, CDKN1B (p27KIP1), CDKN2A (p16INK4), IFNG, PTEN, RB1, TGFB1, TP53.
Autophagy Induction by Intracellular PAthogens: EIF2AK3, IFNG, LAMP1.
Autophagy in Response to Other Intracellular Signals: CTSD, CTSS, DRAM2 (TMEM77), EIF4G1, ESR1 (ERa), GAA, HGS, MAPK14, PIK3C3 (VPS34), PIK3R4, RPS6KB1, TMEM74, ULK2, UVRAG.
Chaperone-Mediated Autophagy: HSP90AA1, HSPA8