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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名:
Histone H2AX Antibody,H2AFX,H2A/X,H2A.X,H2AX,H2a/x
- 克隆性:
多克隆
- 保存条件:
见包装
- 规格:
100 ul
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文献和实验Histone H2AX Phosphorylation: A Marker for DNA Damage
) are generated that rapidly result in the phosphorylation of histone H2A variant H2AX. Because phosphorylation of H2AX at Ser 139 (γ-H2AX) is abundant, fast, and correlates well with each DSB, it is the most sensitive marker that can be used to examine the DNA
Phosphorylation of histone H2AX on Ser 139 is a sensitive reporter of DNA damage, particularly if the damage involves induction of DNA double-strand breaks (DSBs). Phosphorylated H2AX has been named γH2AX and its presence in the nucleus
-H2AX Detection in Somatic and Germ Cells of Mice
The phosphorylation of histone H2AX at serine 139 (γ-H2AX) is one of the first steps of DNA damage response and its detection is widely used as a sensitive marker for DNA double-strand breaks induced by ionizing radiation or other genotoxic
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