CD357(GITR) Antibody-PE；流式抗体；C

产品名称 ：CD357(GITR) Antibody-PE；流式抗体；Clone number：DTA-1
克隆类型 ：Rat Monoclonal Antibody；Clone number：DTA-1
货 号 ：HT1610433
规 格 ：50/500 μg ;
亚 型 ：
Rat IgG2b
浓 度 ：
Concentration：0.2 mg/ml
缓 冲 液 ：
PBS pH 7.2, 0.09% NaN3, 0.2% BSA
产品描述 ：
GITR, Glucocorticoid-induced TNFR-related gene, is a member of the TNF receptor superfamily, also known as TNFRSF18, and AITR (in humans). It is expressed at low levels on resting T lymphocytes and at high levels on CD4+CD25+ T regulatory (Treg) cells. The expression of GITR on T cells can be upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production, as well as MAPKs and NF-κB activation, and abrogate the inhibitory functions of CD4+CD25+ Treg cells. In vivo activation GITR causes development of autoimmune diseases and restores the suppressed immune responses.
适用物种 ：
Mouse
应用范围 ：
FC
应用说明 ：
The amount of the reagent is suggested to be used ≤ 0.25 µg /10^6 cells in 100 µl
保存条件 ：
Store at 4°C and protected from prolonged exposure to light. Do not freeze.
标 记 物 ：
PE（其他荧光标记请咨询我们）