- ￥900 - 1800
- 华拓生物
- 中国
- HT1610427
- 2025年07月16日
- FC
- Rat
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD357(GITR)
- 亚型：
Rat IgG2b
- 形态：
PBS pH 7.2, 0.09% NaN3, 0.2% BSA
- 保存条件：
Store at 4°C and protected from prolonged exposure to light. Do not freeze.
- 克隆性：
Monoclonal Antibody
- 标记物：
BIOT
- 适应物种：
Mouse
- 宿主：
Rat
- 应用范围：
FC
- 浓度：
Concentration：0.5 mg/ml
- 靶点：
Clone number：DTA-1
- 抗体英文名：
CD357(GITR) Antibody-BIOT；流式抗体
- 抗体名：
CD357(GITR) Antibody-BIOT；流式抗体
- 规格：
50/500 μg
克隆类型 ：Rat Monoclonal Antibody；Clone number：DTA-1
货 号 ：HT1610427
规 格 ：50/500 μg ;
亚 型 ：
Rat IgG2b
浓 度 ：
Concentration：0.5 mg/ml
缓 冲 液 ：
PBS pH 7.2, 0.09% NaN3, 0.2% BSA
产品描述 ：
GITR, Glucocorticoid-induced TNFR-related gene, is a member of the TNF receptor superfamily, also known as TNFRSF18, and AITR (in humans). It is expressed at low levels on resting T lymphocytes and at high levels on CD4+CD25+ T regulatory (Treg) cells. The expression of GITR on T cells can be upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production, as well as MAPKs and NF-κB activation, and abrogate the inhibitory functions of CD4+CD25+ Treg cells. In vivo activation GITR causes development of autoimmune diseases and restores the suppressed immune responses.
适用物种 ：
Mouse
应用范围 ：
FC
应用说明 ：
The amount of the reagent is suggested to be used ≤ 0.25 µg /10^6 cells in 100 µl
保存条件 ：
Store at 4°C and protected from prolonged exposure to light. Do not freeze.
标 记 物 ：
BIOT（其他荧光标记请咨询我们）
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文献和实验Human CD4+CD25highCD127low/neg Regulatory T Cells
25, CD39/CD73, CD62L, CD45RO, CD127, glucocorticoid-induced tumor necrosis factor receptor (GITR), CTLA-4, and the forkhead/winged helix transcription factor (FOXP3), has been used to characterize Tregs. Tregs suppress T effector responses mainly
T-Cell Activation Using mAb to CD3
splenic T-cells and human peripheral T cells stimulated via CD3. Critical parameters include cell density, antibody titer and activation kinetics. Materials 1X sterile PBS Anti-mouse CD3e, Clone 145-2C11 (Functional Grade, Cat. No. 16
transfer of residual antibody. Vials of Dynabeads® CD3⁄CD28 CTS™ are at negative pressure – liquid must be displaced with air and vice versa. 2) Place one 10 ml vial of Dynabeads® CD3⁄CD28 CTS™ on the MPC-1 for 1 min. 3)
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