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- 详细信息
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
23094-71-5
- 规格:
10 mM * 1 mL/2 mg/5 mg/10 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥4411.0 |
|---|---|---|---|
| 规格: | 2 mg | 产品价格: | ¥1600.0 |
| 规格: | 5 mg | 产品价格: | ¥2600.0 |
| 规格: | 10 mg | 产品价格: | ¥4200.0 |
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Chebulagic acid
CAS No. : 23094-71-5
MCE 国际站:Chebulagic acid
产品活性:Chebulagic acid是一个从果实中提取出来的 COX-LOX 双重抑制剂。有抗炎和抗感染的效果。Chebulagic acid 是一种 M2(S31N) 抑制剂和抗流感病毒剂。Chebulagic acid 还抑制 SARS-CoV-2 病毒的复制,EC50 值为 9.76 μM.
研究领域:Immunology/Inflammation | Metabolic Enzyme/Protease | Anti-infection
作用靶点:COX | Lipoxygenase | SARS-CoV | Influenza Virus
In Vitro: Chebulagic acid can enhance the autophagy. Chebulagic acid exert anti-inflammatory and anti-infective effects. Chebulagic acid also shows a protective effect against 1-methyl-4-phenylpyridinium (MPP+)-induce cytotoxicity which mimics the pathological symptom of Parkinson's disease. Chebulagic acid inhibits the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner. Furthermore, LPS-activated MAPK signaling is inhibited by Chebulagic acid treatment in the EA.hy926 cells.
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