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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
23094-71-5
- 规格：
10 mM * 1 mL/2 mg/5 mg/10 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥4411.0 |
|---|---|---|---|
| 规格： | 2 mg | 产品价格： | ￥1600.0 |
| 规格： | 5 mg | 产品价格： | ￥2600.0 |
| 规格： | 10 mg | 产品价格： | ￥4200.0 |
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Chebulagic acid
CAS No. : 23094-71-5
MCE 国际站：Chebulagic acid
产品活性：Chebulagic acid是一个从果实中提取出来的 COX-LOX 双重抑制剂。有抗炎和抗感染的效果。Chebulagic acid 是一种 M2(S31N) 抑制剂和抗流感病毒剂。Chebulagic acid 还抑制 SARS-CoV-2 病毒的复制，EC50 值为 9.76 μM.
研究领域：Immunology/Inflammation | Metabolic Enzyme/Protease | Anti-infection
作用靶点：COX | Lipoxygenase | SARS-CoV | Influenza Virus
In Vitro: Chebulagic acid can enhance the autophagy. Chebulagic acid exert anti-inflammatory and anti-infective effects. Chebulagic acid also shows a protective effect against 1-methyl-4-phenylpyridinium (MPP+)-induce cytotoxicity which mimics the pathological symptom of Parkinson's disease. Chebulagic acid inhibits the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner. Furthermore, LPS-activated MAPK signaling is inhibited by Chebulagic acid treatment in the EA.hy926 cells.
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文献和实验.5 Formic acid HCOOH 46.02 90% 23.4 1080 1.20 42.7 Hydrochloric acid HCl 36.5 36% 11.6 424 1.18 86.2 10% 2.9 105 1.05 344.8 Nitric acid HNO3 63.02 71% 15.99 1008 1.42 62.5 67% 14.9 938 1.40 67.1 61% 13.3 837 1.37
浅析染色质免疫沉淀（ChIP）技术在 DNA 与蛋白质相互作用研究中的重要性
-9 and nuclear receptor TLX in neural stem cell fate determination. Nat Struct Mol Biol, 2009. 16(4): p. 365-71. [10] Israsena, N., et al., The presence of FGF2 signaling determines whether beta-catenin exerts effects on proliferation or neuronal differentiation
的酿酒酵母的分泌信号—α交配因子(α-factor)引导序列已经成功地引导了几种外源蛋白的分泌。分泌表达载体主要有：pPIC9，pPIC9K，pHIL-S1，pPICZα A，pYAM75P等。胞内表达载体主要有：pHIL-D2，pA0815，pPIC3K，pPICZ，pHWO10，pGAPZ， pGAPZa(Invitrogen)，pPIC3.5K等。工程菌株Y11430，MG1003，GS115 (AOX1)，KM71，SMD1168。毕赤酵母宿主菌常用的有GS115和KM71两种，都具有
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