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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
Homotaurine; 3-Amino-1-propanesulfonic acid
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
3687-18-1
- 规格:
10 mM * 1 mL/500 mg/1 g/5 g
| 规格: | 10 mM * 1 mL | 产品价格: | ¥385.0 |
|---|---|---|---|
| 规格: | 500 mg | 产品价格: | ¥350.0 |
| 规格: | 1 g | 产品价格: | ¥400.0 |
| 规格: | 5 g | 产品价格: | ¥950.0 |
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Tramiprosate
CAS No. : 3687-18-1
MCE 国际站:Tramiprosate
产品活性:Tramiprosate (Homotaurine),一种具有口服活性和可透过血脑屏障的天然氨基酸,存在于各种红色海藻中。Tramiprosate 与可溶性 Aβ 结合并以非原纤维形式维持 Aβ。Tramiprosate 还是一种 GABA 类似物,具有神经保护,抗惊厥和抗高血压的作用。
研究领域:Neuronal Signaling
作用靶点:Amyloid-β
In Vitro: Tramiprosate (200 μg/mL, 40 μg/mL, 8 μg/mL and 1.6 μg/mL; 1 hours) significantly attenuates oxygen/glucose deprivation (OGD)- or NMDA-induced injury in NGF-differentiated PC12 cells and primary cortical neurons. Tramiprosate decreases the intensity of the association between nNOS and PSD95, and Tramiprosate also inhibits the translocation of nNOS from the cytosol to the membrane.
In Vivo: Tramiprosate (6.25-50 mg/kg; intraperitoneal injection; once) treatment dose-dependently reduces the infarct volume after MCAO. Tramiprosate (50 mg/kg) treatment shows a significant neurological functional recovery.
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文献和实验不同,不同厂商供应的Taq DNA聚合酶性能也有所不同。 Cetus公司酶定义是:1个酶单位是指在以下分析条件下,于74℃,30min内使10nmmol的dNTP掺入酸不溶性成分所需的酶。测定时间为10min,折算成30min掺入量。 分析条件为25nmol/L TAPS(三羟基-甲基-氨基丙烷磺酸钠pH9.3,25℃),50mmol/l KCl, 2mmol/L MgCl2 ,1mmol/L β-ME(巯基乙醇),dATP、dTTP、dGTP各200mmol/L,dCTP为100
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