- 询价
- Cell Signaling Technology
- 4041
- USA
- 2025年09月08日
- W, F
- H
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
CD44 (156-3C11) Mouse mAb (Biotinylated)
- 抗原：
stimulated human leukocytes
- 应用范围：
W, F
- 级别：
详见MSDS文件
- 保质期：
详见说明书
- 适应物种：
H
- 供应商：
CST
- 库存：
大量
- 是否单克隆：
1
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting F=Flow Cytometry
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
|---|---|---|---|---|
| W F | H | Endogenous | 80 | Mouse IgG2a |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | CD44 (156-3C11) Mouse mAb (Biotinylated) detects endogenous levels of total CD44 protein. |
| Source / Purification | Monoclonal antibody is produced by immunizing BALB/c mice with stimulated human leukocytes. Western Blotting
Western blot analysis of extracts from HeLa and PANC-1 cells using CD44 (156-3C11) Mouse mAb (Biotinylated) and developed using Streptavidin-HRP #3999. Flow Cytometry
Flow cytometric analysis of HeLa cells using CD44 (156-3C11) Mouse mAb (Biotinylated) (blue) compared to Mouse (MOPC-21) mAb IgG1 Isotype Control (Biotinylated) #4097 (red). |
| Description | This Cell Signaling Technology antibody is conjugated to biotin under optimal conditions. The biotinylated antibody exhibits the same species cross-reactivity as the unconjugated CD44 (156-3C11) Mouse mAb #3570. |
| Background | CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interaction through its affinity for hyaluronic acid (HA) and possibly through other parts of the extracellular matrix (ECM). CD44 is highly polymorphic, possesses a number of alternative splice variants and undergoes extensive post-translational modifications (1,2). Increased surface levels of CD44 are characteristic of T cell activation, and expression of the protein is upregulated during the inflammatory response. Interactions between CD44 and HER2 have been linked to an increase in ovarian carcinoma cell growth (1-3). CD44 interacts with ezrin, radixin and moesin (ERM), linking the actin cytoskeleton to the plasma membrane and the ECM (4-6). CD44 is constitutively phosphorylated at Ser325 in resting cells. Activation of PKC results in phosphorylation of Ser291, dephosphorylation of Ser325, disassociation of ezrin from CD44, and directional motility (4).
|
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验T-Cell Activation Using mAb to CD3
splenic T-cells and human peripheral T cells stimulated via CD3. Critical parameters include cell density, antibody titer and activation kinetics. Materials 1X sterile PBS Anti-mouse CD3e, Clone 145-2C11 (Functional Grade, Cat. No. 16
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 大鼠可溶性 CD44(sCD44)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗大鼠 sCD44 单抗包被于酶标板上，标准品和样品中的 sCD44 与单抗结合，加入生物素化的抗大鼠 sCD44 ，形成免疫
人可溶性CD44v6(sCD44v6)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人可溶性CD44v6 (sCD44v6)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 sCD44v6 单抗包被于酶标板上，标准品和样品中的 sCD44v6与单抗结合，加入生物素化的抗人
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