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- ￥7300
- GeneTex
- 美国
- GTX84182
- 2026年05月27日
- WB, ICC/IF, IHC-P
- Mouse
- Human
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- 文献和实验
- 技术资料
- 免疫原：
Human recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cell.
- 亚型：
IgG1
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX84182
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Mouse
- 应用范围：
WB, ICC/IF, IHC-P
- 浓度：
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点：
LOX
- 抗体英文名：
LOX antibody [6B11]
- 抗体名：
LOX 抗体 [6B11]
- 规格：
100 μl
IHC-P analysis of human colon tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
IHC-P analysis of human pancreas tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
IHC-P analysis of human bladder carcinoma tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
IHC-P analysis of human prostate carcinoma tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
IHC-P analysis of human prostate tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
ICC/IF analysis of COS7 cells transiently transfected with LOX plasmid using GTX84182 LOX antibody [6B11].
IHC-P analysis of human breast adenocarcinoma tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
IHC-P analysis of human liver tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
IHC-P analysis of human endometrium tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
IHC-P analysis of human thyroid tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
IHC-P analysis of human ovary adenocarcinoma tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
IHC-P analysis of human kidney tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
WB analysis of HEK293T cells transfected with LOX plasmid (Right) or empty vector (Left) for 48 hrs using GTX84182 LOX antibody [6B11].
Loading : 5 ug per lane
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文献和实验Goggins E et al., Neoplasia 2017 (PMID:29247885)
Wang C et al., Biotechnol Lett 2020 (PMID:32358726)
OLR1（LOX-1）配体结合机制、胞内信号调控及蛋白试剂应用解析
。此外，OLR1在多种免疫及特定功能细胞中也广泛存在，包括单核吞噬细胞、中性粒细胞、树突状细胞、滋养层细胞以及胶质细胞。这种广泛的分布模式提示OLR1不仅在血管生物学中发挥作用，还深度参与了免疫调节及神经系统的生理过程。 OLR1的结构和其受体 OLR1（又称LOX-1）是一种属于C型凝集素超家族的II型跨膜糖蛋白，分子量约50-52 kDa，由273个氨基酸组成。其结构主要包含三个部分：N端的短胞质尾区、跨膜结构域以及C端的胞外凝集素样结构域，后者是识别配体的关键区域。作为受体，OLR1的主要配体是氧
mTn-3xHA/lacZ TR Tn3 terminal inverted repeats Xa Factor Xa cleavage recognition site loxR lox site, target for Cre recombinase
mTn-3xHA/GFP TR Tn3 terminal inverted repeats Xa Factor Xa cleavage recognition site loxR lox site, target for Cre recombinase
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