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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant protein encompassing a sequence within the center region of human Neuregulin-1. The exact sequence is proprietary.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX101117
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
WB, ICC/IF
- 浓度:
0.96 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
Neuregulin-1
- 抗体英文名:
Neuregulin-1 antibody
- 抗体名:
Neuregulin-1 抗体
- 规格:
100 μl/25 μl
| 规格: | 100 μl | 产品价格: | ¥4000.0 |
|---|---|---|---|
| 规格: | 25 μl | 产品价格: | ¥1700.0 |
Rat tissue extract (50 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with Neuregulin-1 antibody (GTX101117) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Neuregulin-1 antibody detects Neuregulin-1 protein at nucleus by immunofluorescent analysis.
Sample: SK-N-SH cells were fixed in 4% PFA at RT for 15 min.
Green: Neuregulin-1 protein stained by Neuregulin-1 antibody (GTX101117) diluted at 1:500.
Red: Phalloidin, a cytoskeleton marker, diluted at 1:100.
Blue: Hoechst 33342 staining.
Sample (50 μg of whole cell lysate)
A: mouse brain
7.5% SDS PAGE
GTX101117 diluted at 1:1000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Human tissue extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with Neuregulin-1 antibody (GTX101117) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
U87-MG whole cell extract and conditioned medium (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Neuregulin-1 antibody (GTX101117) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
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文献和实验Casagrande V et al., Sci Rep 2017 (PMID:28751722)
Modeling Schizophrenia in Neuregulin 1 and ErbB4 Mutant Mice
. However, genetic studies have recently identified many susceptibility genes of this disorder including neuregulin 1 (NRG1 ) and its receptor ErbB4 . Arguably, relevant mutant mice have provided a unique opportunity to model “schizophrenia” in animals
可以作用于几个NRG。 bigqi 在pubmed的mesh中也找不到NRG β1. 在文章里找到这样一句话: ...soluble ErbB ligands from the β-exon-containing type I neuregulin-1a protein (also called heregulin, glial growth factor, or ARIA), which we call NRG β1. 名字是他起的?按字面
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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