- ￥9000
- GeneTex
- 美国
- GTX54842
- 2025年07月12日
- WB, ICC/IF, IHC-Fr
- Rabbit
- Human, Mouse, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Peptide CIANHTGVDIHRNGDFQKNG, corresponding to amino acid residues 1042-1061 (Intracellular loop between domains II and III) of rat NaV1.6 (Accession : O88420).
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse, Rat
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Rat
- 目录编号：
GTX54842
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Rabbit
- 应用范围：
WB, ICC/IF, IHC-Fr
- 浓度：
0.8 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点：
Nav1.6
- 抗体英文名：
Nav1.6 antibody
- 抗体名：
Nav1.6 抗体
- 规格：
50 μl
ICC/IF analysis of PFA-fixed rat DRG primary cells using GTX54842 Nav1.6 antibody.
Panel A : Primary antibody
Panel B : DNA dye Hoechst 33342
Panel C : Merged images of panels A and B
Dilution : 1:200
WB analysis of rat brain membrane lysates using GTX54842 Nav1.6 antibody preincubated with or without immunogen peptide.
Dilution : 1:200
IHC-Fr analysis of mouse hippocampus tissue using GTX54842 Nav1.6 antibody. DAPI is used as the counterstain.
Panel A : NaV1.6 (green) is robustly expressed in the CA1 pyramidal layer (white arrows).
Panel B : Staining with mouse anti-parvalbumin (red), a marker of interneurons.
Panel C : Merged image of panels A and B reveals that NaV1.6 appears in some interneurons (arrow) but is not restricted to interneurons.
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文献和实验S?nchez-Aguilera A et al., Neuroscience 2020 (PMID:32634531)
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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