- 询价
- Cell Signaling Technology
- 9843
- USA
- 2026年01月11日
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赛信通（上海）生物试剂有限公司暨美国CST中国分公司
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600 ug
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文献和实验Assays for HSP90 and Inhibitors
of HSP90 inhibitors have already been identified. These include the benzoquinone ansamycin natural product geldanamycin and its analog, 17-allylamino-17-demethoxy-geldanamycin (17AAG), together with the chemically dissimilar natural product radicicol
GPC Spin Column HPLCESI-MS Methods for Screening Drugs Noncovalently Bound to Proteins
are fully described. The GPC spin column HPLC–ESI-MS methodology for screening of drugs non-covalently bound to proteins is illustrated for the non-covalent binding of geldanamycin with Hsp90cat protein.
More Than One Way to Die: Methods to Determine TNF-Induced Apoptosis and Necrosis
apoptotically, because triggering of Fas in L929sAhFas cells leads to apoptosis. Moreover, TNFR-1-induced necrosis can be reverted to apoptosis when cells are pretreated with geldanamycin, an Hsp90 inhibitor. In contrast, addition of caspase-inhibitors (zVAD-fmk
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