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- Cell Signaling Technology
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- USA
- 2026年01月13日
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赛信通（上海）生物试剂有限公司暨美国CST中国分公司
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文献和实验Analysis of Androgen Receptor Rapid Actions in Cellular Signaling Pathways: Receptor/Src Association
activation of the Src/Ras/Erk pathway and finally impacts cell cycle. Androgen stimulation of fibroblasts also induces AR/Src association, which triggers DNA synthesis. Prevention of this association by a receptor-derived peptide competing for AR interaction
Use of Peptide Libraries to Determine Optimal Substrates of Tyrosine Kinases
substrates is mfluenced by interactions with noncatalytic regions of the enzymes such as autophosphorylation sites, Src homology 2 (SH2) domains, and Src homology 3 (SH3) domains. These interactions may recruit substrates to the vicinity of the tyrosme kinase
Mapping the Specificity of SH3 Domains with Phage-Displayed Random-Peptide Libraries
. These protein-protein interactions are often mediated by conserved-modular domains, such as the Src Homology domains 2 and 3, known as SH2 and SH3 (1 ,2 ). Recently, combmatorral-peptrde libraries have been used to define high-affinity peptide ligands
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